Sarah Wong-Goodrich, Ph.D.

Dr. Sarah Wong-Goodrich teaches courses in introductory psychology, introductory statistics, research methods, brain and behavior, and hormones and behavior. Her current research interests include extending animal models of learning and memory to humans, with a specific interest in the functional contribution of adult hippocampal neurogenesis to human memory. Dr. Wong-Goodrich’s research and publications have focused on various animal models to investigate the regulation and neural substrates of learning and memory in both healthy and diseased states, with a specific emphasis on hippocampal function and plasticity.

• Wong-Goodrich, S.J.E., King, S.G., Mellot, T.J., Blusztajn, J.K., & Williams, C.L. (in preparation). Prenatal choline availability regulates delay matching-to-place working memory and adult neurogenesis in the hippocampus and olfactory bulb.
• Wong-Goodrich, S.J.E. & Kee, D.W. (in preparation). Variation in cognitive performance and cerebral hemispheric asymmetry across the human menstrual cycle in normal cycling females.
• Smart, D., Garcia-Glaessner, A., Palmieri, D., Wong-Goodrich, S., Kramp, T., Gril, B., Reed, T., Qian,Y., Hua, E., Cameron, H.A., Shukla, S., Camphausen, K., & Steeg, P.S. (2015). Analysis of radiation therapy in a model of triple-negative breast cancer brain metastasis. Clinical      Experimental Metastasis, 32, 717-727.
• Wong-Goodrich, S.J.E., Tognoni, C.M., Mellott, T.J., Glenn, M.J., Blusztajn, J.K., & Williams, C.L. (2011). Prenatal choline deficiency does not enhance hippocampal vulnerability to seizures in adulthood. Brain Research, 1413, 84-97.
• Wong-Goodrich, S.J.E., Mellott, T.J., Liu, Y.B., Blusztajn, J.K., & Williams, C.L. (2011). Water maze experience and prenatal choline supplementation differentially promote long-term hippocampal recovery from seizures in adulthood. Hippocampus, 21, 584-608.
• Wong-Goodrich, S.J.E., Pfau, M.L., Fraser, J.A., Flores, C.T., Williams, C.L., & Jones, L.W. (2010). Voluntary running after whole-brain irradiation prevents progressive memory decline and increases adult hippocampal neurogenesis and growth factor expression. Cancer Research, 70, 9329-9338.
• McDowell, K.A., Hutchinson, A.N., Wong-Goodrich, S.J.E., Presby, M.M., Su, D., Law, K.C., Williams, C.L., Wetsel, W.C., & West, A.E. (2010). Reduced cortical BDNF expression and aberrant memory in Carf knockout mice. Journal of Neuroscience, 2, 7453-7465.
• Wong-Goodrich, S.J.E., Glenn, M.J., Mellott, T.J., Meck, W.H., Blusztajn, J.K., & Williams, C.L. (2008). Spatial memory and hippocampal plasticity are differentially sensitive to the availability of choline in adulthood as a function of choline supply in utero. Brain Research, Special Issue: Brain, Genes, and Nutrition, 1237, 152-166.
• Wong-Goodrich, S.J.E., Mellott, T.J., Glenn, M.J., Blusztajn, J.K., & Williams, C.L. (2008). Prenatal choline supplementation attenuates neuropathological response to status epilepticus in the adult hippocampus. Neurobiology of Disease, 30, 255-269.
• Glenn, M.J., Kirby, E.D., Gibson, E.M., Wong-Goodrich, S., Mellott, T.J., Blusztajn, J.K., & Williams, C.L. (2008). Age-related declines in exploratory behavior and markers of hippocampal plasticity are attenuated by prenatal choline supplementation in rats. Brain Research, Special Issue: Brain, Genes, and Nutrition, 1237, 110-123.

• Ganguly, A., Troy, E.L., McEwen, C.A., Wong-Goodrich, S.J.E., Huang, Z., Iaci, J., Colburn, R.W., Caggiano, A.O., & Parry, T.J. (November, 2013). Glial growth factor-2 treatment improves locomotor and bladder function following spinal cord injury in adult rats. Poster presented at the annual meeting of the Society for Neuroscience, San Diego, CA.
• McEwen, C.A., Wong-Goodrich, S.J.E., Huang, Z., Troy, E.L., Ganguly, A., R.W., Caggiano, A.O., & Parry, T.J. (November, 2013). Measures of long-term neurological recovery differentially affected by stroke severity in an intraluminal filament MCAO model in adult rats. Poster presented at the annual meeting of the Society for Neuroscience, San Diego, CA.
• McEwen, C., Troy, E., Wong-Goodrich, S, Ganguly, A., Caggiano, A.O., Schallert, T., & Parry, T. (2012, October). Strain-dependent sensorimotor functional recovery following sciatic nerve injury across multiple rat strains. Poster presented at the annual meeting of the Society for Neuroscience, New Orleans, LA.
• Wong-Goodrich, S.J.E., Soumier, A.F., Grigereit, L.E., Sowers, A.L., Mitchell, J.B., & Cameron, H.A. (2011, November). Protection against whole-brain irradiation impairment of dentate gyrus dependent metric memory by tempol pretreatment. Poster presented annual meeting of the  Society for Neuroscience, Washington, DC.
• Wong-Goodrich, S.J.E., Pfau, M.L., Flores, C., Jones, L.W., & Williams, C.L. (2009, October). Exercise promotes recovery from cognitive dysfunction, depressive-like behavior, and loss of hippocampal neurogenesis following whole-brain irradiation in adult mice. Poster presented at the annual meeting of the Society for Neuroscience, Chicago, IL.
• Williams, C.L., Wong-Goodrich, S.J.E., Mellott, T.J., Liu, Y.B., Blusztajn, J.K. (2009, October). Repeated water maze experience and/or prenatal choline supplementation aid recovery of spatial learning and memory and long-term declines in hippocampal plasticity following seizures. Poster presented at the annual meeting of the Society for Neuroscience, Chicago, IL.
• Wong-Goodrich, S.J.E., Glenn, M.J., Mellott, T.J., Meck, W.H., Blusztajn, J.K., & Williams, C.L. (2008, November). Differential sensitive of spatial memory and hippocampal plasticity to dietary choline supply in adulthood as a function of prenatal choline availability. Poster presented at the annual meeting of the Society for Neuroscience, Washington, D.C.
• Wong-Goodrich, S.J.E., Glenn, M.J., Mellott, T.J., Meck, W.H., Blusztajn, J.K., & Williams, C.L. (2008, May). Hippocampal spatial memory and plasticity are differentially sensitive to the availability of choline in adulthood as a function of choline supply in utero. Poster presented at the Multidisciplinary Workshop on Nutrition, Brain Development, and Aging, Kannapolis, NC.
• Wong-Goodrich, S.J.E., Glenn, M.J., Mellott, T.J., Blusztajn, J.K., & Williams, C.L. (2007, November). Interactive effects of prenatal choline supplementation and water maze training: Implications for long-term consequences of status epilepticus. Poster presented at the annual meeting of the Society for Neuroscience, San Diego, CA.
• Wong-Goodrich, S.J.E., McCool, K., Glenn, M.J., Mellott, T.J., Blusztajn, J.K., & Williams, C.L. (2007, June). Motherhood’s enhancement of hippocampal plasticity requires pregnancy and lactation in addition to interaction with pups. Poster presented at the annual meeting of the Society for Behavioral Neuroendocrinology, Monteray Bay, CA.
• Glenn, M.J., McCool, K., Wong-Goodrich, S.J., Mellott, T.J., Blusztajn, J.K., & Williams, C.L. (2007, June). Both pregnancy and lactation/pup rearing are required for motherhood-induced increases in hippocampal plasticity. Poster presented at the Parental Brain Conference, Boston, MA.
• Wong-Goodrich, S.J.E. & Kee, D.W. (2006, June). Variation in cognitive and cerebral hemispheric function across the menstrual cycle in normal cycling females. Poster presented at the annual meeting of the Society for Behavioral Neuroendocrinology, Pittsburgh, PA.
• Fraser, J.F., Wong-Goodrich, S.J.E., Williams, C.L., & Glenn, M.J. (2006, June). Motherhood induces both short and long-term improvements in spatial working memory that is accompanied by changes in hippocampal cell proliferation. Poster presented at the annual meeting of the Society for Behavioral Neuroendocrinology, Pittsburgh, PA.
• Glenn, M.J., Kirby, E.D., Wong-Goodrich, S.J.E., & Williams, C.L. (2006, May). Supplemental choline in the maternal diet of rats modulates hippocampal neurogenesis and exploratory behavior in offspring. Poster presented at the annual meeting of the International Behavioral Neuroscience Society, Whistler, British Columbia, Canada.
• Wong-Goodrich, S.J.E., Glenn, M.J., Mellott, T.J, Blusztajn, J.K., & Williams, C.L. (2006, October). Prenatal choline supplementation attenuates response to status epilepticus in the adult hippocampus. Poster presented at the annual meeting of the Society for Neuroscience, Atlanta, GA.
• Williams, C.L., Fraser, J.A., Wong-Goodrich, S.J.E., & Glenn, M.J. (2006, October). Motherhood is an "enriching" experience: post-weaning upregulation of hippocampal neurogenesis and improvement in spatial working memory in the primiparous rat. Poster presented at the annual meeting of the Society for Neuroscience, Atlanta, GA.
• Wong-Goodrich, S., Morrow, J., Walsh, S., Harris, A., & Trevitt, J. (October, 2005). Adenosine antagonists reverse haloperidol-induced suppression of lever pressing: Implications for Parkinson’s disease. Poster presented at the annual meeting of the Society for Neuroscience, Washington, D.C.
• Wong-Goodrich, S., Morrow, J., Ruiz, I., Florian, F., & Trevitt, J. (May, 2005). Caffeine reverses suppression of lever pressing in animal model of Parkinson’s disease. Poster presented at the annual meeting of the American Psychological Society, Los Angeles, CA.
• Kirk, K., Wong-Goodrich, S., & Kee, D. (2004, July). Cerebral hemisphere specialization in a picture word naming task. Poster presented at the annual meeting of the American Psychological Association, Honolulu, HI.
• Plaxton-Hennings, C., Wong-Goodrich, S., Nicastro, S., Brown, J., Reed, E., & Zaha, N. (2003, June). Religiosity and eating disorders. Paper presented at the annual meeting of the Christian Association for Psychological Studies, Anaheim, CA.
• Plaxton-Hennings, C., Wong-Goodrich, S., Nicastro, S., Brown, J., Reed, E., & Zaha, N. (2004, April). The effects of stress on immune functioning in college students. Poster presented at the annual meeting of the Western Psychological Association, Phoenix, AZ.